IDENTIFICATION OF RESIDUES OF SARS-COV NSP1 THAT DIFFERENTIALLY AFFECT INHIBITION OF GENE EXPRESSION AND ANTIVIRAL SIGNALING.

Identification of residues of SARS-CoV nsp1 that differentially affect inhibition of gene expression and antiviral signaling.

An epidemic of Severe Acute Respiratory Syndrome (SARS) led to the identification of an associated coronavirus, SARS-CoV.This virus evades the host innate immune response in part through the expression of its non-structural protein (nsp) 1, which inhibits both host gene expression and Amber virus- and interferon (IFN)-dependent signaling.Thus, nsp1

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Anekdoot kui niisugune

The lexicon of foreign words defines the anecdote as a short, interesting, often invented, but striking story of some funny encounter.Actually, this definition says practically nothing about the anecdote and is wrong and incomplete, too.Anecdote is a collective folk creation, except for maybe absurd anecdotes.Anecdotes come to be in the process of

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Nanotechnology in Plant Science: To Make a Long Story Short

This mini-review aims at gaining knowledge on basic aspects of plant nanotechnology.While in recent years the enormous progress of nanotechnology in biomedical sciences has revolutionized therapeutic and diagnostic approaches, the comprehension of nanoparticle-plant interactions, including uptake, mobilization and accumulation, is still in its infa

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The Complexity of Skeletal Transverse Dimension: From Diagnosis, Management, and Treatment Strategies to the Application of Collaborative Cross (CC) Mouse Model

This study investigates the significance of skeletal transverse dimension (STD) in orthodontic therapy and its impact on occlusal relationships.The primary goal is to enhance understanding and promote the integration of transverse skeletal diagnostics into routine orthodontic assessments.To achieve this aim, the study employs a comprehensive approa

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